Gestational iron deficiency and brain development

Lozoff B. & Georgieff, M. Pediatric Neurology, 2006; 13: 158-165.

Iron deficiency is one of the most common mineral deficiencies in pregnant women and infants worldwide.

Infants with iron deficiency anaemia test lower in cognitive, motor, social-emotional and neurophysiologic development than comparison group infants.

Iron deficiency during gestation and lactation alters neurometabolism, neurotransmitters, myelination, and gene/protein profiles before and after iron repletion at weaning.

Randomised trials of iron supplementation show benefits which emphasises the importance of protecting the developing brain from iron deficiency.